Overview of weight loss drug
The weight loss drug
Answer inhibitors: This drug reduces appetite and makes individuals full for a longer period of time to eat less calories.
Lipase inhibitors: These drugs are ultimately reduced liposuction by blocking the action of lipase enzymes that break down and absorb fat.
Hormonal modulator: This drug targets hormones associated with metabolic regulation, such as thyroid function or insulin levels.
Prescribed weight loss drug
Orlistat (Xenical): Orlistat is a lipase inhibitor approved for long-term use. It works by blocking about 30%of the dietary fat intake. Along with exercise, it shows promising results of weight loss.
Liraglutide (SAXENDA): Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor that helps to control blood sugar levels and appetite. It is prescribed to individuals with companion diseases such as diabetes, hypertension or high cholesterol.
CONTRAVE: Naltrexon is an opioid receptor antagonist that acts as an appetite inhibitor. It has been approved for a long-term use with another antidepressant, Burpropion. Shows promising results.
PHENTERMINE (Adipex-P): Phentrermine is an appetite inhibitor that stimulates the central nervous system. It is prescribed.
Safety and side effects
Miss weight loss drugs can cause a variety of side effects depending on certain drugs, doses, and individual health. Patients who consider these drugs are essential to discuss potential risks and benefits with medical service providers before starting treatment. The general side effects include:
Orlistat: camouflage problems such as oiled chairs, gas and diarrhea.
Liraglutide: hypoglycemia, nausea and constipation.
Naltrexon: Headache, depression and heart rate increase.
Pentermine: Blood pressure, headache and anxiety.
Efficacy Comparison of Weight Loss Medications - Best Prescribed Options
Several weight loss drugs are available, and each has distinct action mechanisms and efficacy, and this article will focus on the most defined options such as Orlistat, Phentermine, Liraglutide and Semaglutide.
Orlistat (xenical) is a gastrointestinal lipase inhibitor that blocks the absorption of fat. It is shown to reduce fat intake by about 30% and cause weight reduction in clinical trials. The average weight loss was 10.2%compared to 6.7%of the group, and long-term studies showed that the effect of Orlistat remained over time and the benefits lasted for up to four years.
ADIPEX-P is an amphetamine-like stimulus that acts as an appetite inhibitor by increasing the sympathetic nervous system activity. Compared to the 3.6% weight loss, it has lost 7.5% of the initial weight, but its efficacy tends to decrease over time, and long-term use is limited due to potential side effects such as increased blood pressure and heart rate.
Liraglutide (SAXENDA) is a glucagon-like peptide-1 (GLP-1) receptor that acts by slowing the stomach discharge and increasing satiety and reducing food intake. Clinical trials have proved significant weight reduction in liragluide treatment. In the 56-week study, patients with Liraglutite have experienced an average weight loss of 8%compared to 2.5%of the placebo group, and Liragluthide is also associated with improvement of other metabolic parameters, such as blood glucose control and lipid levels.
SEMAGLUTIDE (Wegovy) is another GLP-1 receptor agent that shares a similar action mechanism to Lira gluteide, but has a long half-life, allowing one week to administer. We have experienced an average weight loss compared to %. The significant difference in efficacy is that we emphasize the semaglutide as a promising option for the treatment of obesity.
Prescribed weight loss drug
Based on the discussed efficacy speed and action mechanisms, Semaglutide seems to be the most effective weight loss drug that is currently available. One dosage and impressive 14.9% average weight loss per week are attractive to patients who want to reduce continuous weight. But to ensure the most appropriate treatment plan, you need to consider the factors and troops for each patient when prescribing weight loss drugs.
Centered Safety and Side Effects of Weight Loss Medications
Safety consideration
It is important to evaluate potential risks and benefits before starting a weight loss related to the drug. In general, weight loss drugs are generally considered safe with healthy lifestyles, including adequate Korean diets and exercise. To check if there are no contraindications or complications, you need to get a thorough medical evaluation before starting the drug.
Most weight loss drugs have been proven to be effective for some individuals, but may cause side effects. Some common side effects include headaches, gastrointestinal problems (constipation, diarrhea or nausea), dizziness and heart rate increase. Or more serious side effects such as psychiatric symptoms such as depression.
Prescribed weight loss drug
Orlistat: Orlistat is a FDA approval drug used for weight loss of overweight and obese adults. It includes a reduction in the body's ability to absorb.
LORCASERIN: Lorcaserin is another FDA weight loss drug that acts as an appetite inhibitor. It helps to control hunger and filling signals by targeting the serotonin receptor of the brain. It is included.
PHENTERMINE: Phentrermine is an older prescription appetite inhibitor used to reduce short-term weight in obesity patients. It works by stimulating the central nervous system and reducing appetite.
SEMAGLUTIDE: Semaglutide, recently approved by the FDA, is a weekly injection drug that acts as a glucagon-like peptide-1 (GLP-1) receptor. The nausea, vomiting and diarrhea are included.
Patient Selection Criteria for Weight Loss Medications
Patient selection criteria
Body mass index (BMI): Obesity is defined as BMI of more than 30 kg/m², which guarantees consideration of weight loss mediation. The seriousness of obesity is class I (BMI 30-34.9), Class II (BMI 35-39.9)) And it can be classified into three categories of class III (BMI ≥40). These classification patients can benefit from drug therapy.
Pathology: Obesity individuals often have coexistent medical conditions such as type 2 diabetes, hypertension, abnormal lipidemia or sleep apnea. This conditions can be worsened by obesity, and weight loss is an important factor in health care.
Earlier weight loss attempts: patients who failed lifestyle modifications and other non-pharmacological interventions can benefit from additional treatment options such as drugs to support weight loss.
Psychological evaluation: Mental health plays an important role in weight management. Patients with depression, anxiety or eating disorders must be evaluated before starting the weight loss drug to ensure appropriate choices and compliance.
Pregnancy and breastfeeding: weight loss drugs are generally contraindicated during pregnancy and lactation due to potential damage to fetal or infants. Women with fertility potential should use effective contraception for these drugs.
Prescribed weight loss drug
Orlistat: Orlistat (xenical) is a gastrointestinal lipase inhibitor that reduces lipok absorption and causes weight loss. BMI ≥30 kg/m² adults or BMI ≥ 27 kg/m² and hypertension, type 2 diabetes or abnormal lipidemiaIt is recommended for adults with the same other risk factors.
Lorcaserin: Lorcaserin (BelviQ) is an optional serotonin receptor agent that promotes only and reduces food intake. It is displayed on adults with other risk factors.
PHENTERMINE: Phentrermine (Adipex-P) is an appetite inhibitor that acts on the central nervous system to reduce hunger. BMI ≥30 kg/m² adults or BMI ≥ 27 kg/m² and high blood pressure, type 2 diabetes or abnormal lipidemiaIt is recommended for adults with the same other risk factors.
Topiramate: Topiramate (QSYMIA) is an anti-spasm and appetite inhibitor that can be used with pentermine in patients with BMI ≥30 kg/m² or BMI ≥ 27 kg/m² and hypertension, type 2 diabetes patients. Abnormal lipidemia.
The choice of the best-prescribed weight loss drug depends on the patient's individual needs, joint troops, troops, and overall health. The close monitoring of medical professionals is essential for guaranteeing patient safety and optimal treatment results.
Long-Term Effects and Maintenance of Weight Loss
Long-term effects and maintenance of weight loss
There are many advantages to maintain a healthy weight through a consistent weight loss. Some of these organ effects are as follows:
Reduction of risks of chronic diseases: Obesity increases the risk of developing conditions such as type 2 diabetes, cardiovascular disease, hypertension, and certain types of cancer.there is.
Mental Health Improvement: Excessive weight is often associated with depression, anxiety and self-esteem: weight loss can increase confidence, improve mood, and lead to psychological welfare improvement.
Physical performance improvement: As obesity contributes to the reduction of health, maintaining weight loss and maintenance can enhance the energy level, endurance and overall physical performance.
Better sleep quality: Obesity is associated with poor sleep quality, which can lead to numerous health problems. By achieving healthy weight, individuals can improve sleep patterns and overall sleep quality.
Prescribed weight loss drug
Individuals who want effective weight loss solutions under medical professional will provide several drugs. Some of the most prescribed weight loss drugs are as follows:
Orlistat: Orlistat (xenical) is a prescription drug that inhibits fat absorption in the digestive system, which reduces calorie intake and promotes weight loss. Rlistat is effective in inducing weight loss and maintaining over time. It was.
Liraglutide: Liraglutide (Saxenda) is an injection drug belonging to a class called GLP-1 receptor action. It helps to control blood sugar levels, suppress appetite, and promote filling. It has shown that it is effective for maintaining up to two years.
PHENTERMINE: Phenermine is an appetite inhibitor that stimulates the central nervous system to reduce hunger, which is effectively used for short-term weight loss and is generally combined with lifestyle modifications such as diet and exercise.
BUPROPION: BUPROPION (WELLBUTRIN) is an antidepressant drug that functions as an appetite inhibitor. It can be used for weight loss.
Regulatory guidelines
Regulatory authorities, such as the US Food and Drug Administration (FDA) and EMA (EMA), have established strict guidelines for approval of weight loss drugs. These institutions have granted marketing approval before granting marketing approval, safety and risk-interests of drugs before granting marketing approval. Evaluating the profile. FDA has approved several drugs, including Orlistat, PheneTermine, Topiramate, Naltrexone, Liraglutide and Semaglutide for long-term use as part of a comprehensive weight management program.
Prescription guideline
Prescription guidelines vary from country to country, but they usually follow similar principles. They guarantee the proper use of weight loss drugs in consideration of factors such as BMI, troops, companionships and potential risks and benefits associated with each drug. The aim is to considering the willingness to participate in non-pharmacological interventions such as the patient's lifestyle, dietary habits and exercise and behavioral correction.
Prescribed weight loss drug
Some weight loss drugs are possible. However, Semaglutide (trade name) has emerged as the top competitor due to impressive efficacy, long-term effects on safety profiles and weight management. Semaglutide increases saturty, reduces food intake, and is healthy. It is a peptide-1 (GLP-1) receptor agent like glucagon that promotes metabolism.
Clinical trials have been significantly reduced by semagluide treatment for obesity patients, and the average weight loss has decreased by 15-18% for two years. Risk factors have been improved: the most common side effects include camouflage symptoms such as nausea and diarrhea, which usually sinks over time.
